This is a list of events that occurred in 2250:
- Susan Ivanova is involved romantically with Malcolm Biggs. She broke up with him when she was reassigned to the transfer station on Io, an assignment she credits as a "great career move." On Station Io she served under the command of John Sheridan. During her time there, she once tossed a telepath out of a third story window and into a pool below.
- Esparanza Beldon, mother of Alisa Beldon and wife of Eliot Beldon, dies on Earth from Stafford's Plague.
- A young Dr. Morden gives a speech before the Interplanetary Archaeological Society on the misconceptions surrounding Anfran love stones.
- Over EA President Elizabeth Levy's objections, the Earth Senate votes to cut off supply shipments to Mars in retaliation for their declaration of neutrality during the recent Earth-Minbari War.
|Before the Third Age:||20th Century and earlier 21st Century 22nd Century 2200s 2210s 2220s 2230s 2240s|
|2250s:||2250 2251 2252 2253 2254 2255 2256 2257 2258 2259|
|2260s:||2260 2261 2262 2263 2264 2265 2266 2267 2268 2269|
|2270s onwards:||2270s 2280s 2290s 2300s and beyond|