During the Earth Alliance Civil War, Frank commanded the EAS Cadmus. He was one of many who believed the propaganda campaign against Captain John Sheridan. In particular, that he was executing Earthforce crews and replacing them with Minbari. Because of this, Frank and the other Earthforce Captains continued to fight despite being outnumbered, out gunned and with their jump engines down.
In 2261, the Cadmus joined the EAS Hydra and the EAS Delphi to engage Sheridan's forces alongside the Earthforce ships including the EAS Vesta. The Hydra and Delphi stood down, but Frank continued to fight. Sheridan pleaded with him to stand down, and Frank defied him, revealing what he came to believe about him. MacDougan interjected and convinced him he was told lies, as he had been lied to.
The name Leo Frank was inspired by the Jewish man of the same name. Living in Georgia in the early 20th century, he owned the factory where a Christian teenager, Mary Phagan, was murdered. Accused of the crime, the trial featured little evidence and instead focused primarily on his wealth, religion, and Yankee origins. He was convicted and sentenced to death. But when the governor condemned the trial as a miscarriage of justice and commuted his sentence, a group was formed that overran the prison, and then seized and lynched Leo Frank. Called "The Knights of Mary Phagan," the group later initiated a rival of the Ku Klux Klan. Frank was later pardoned posthumously.